Clinical Pharmacology Lead > Joboolo FR :

Role:


Clinical Pharmacology Lead

Location:


Hybrid

- must be able to commit to 2x days per week in Antwerp

The Role

We are seeking a highly Senior Clinical Pharmacology Lead to play a key, senior role in advancing a growing portfolio of innovative small-molecule therapies.


This is a hands-on position with significant scientific ownership, where you will lead clinical pharmacology strategy from early translational development through proof of concept and beyond.


You will act as a core individual contributor while progressively taking on broader leadership responsibilities as the pipeline and organization expand.

The Company

You will join a fast-growing, science-driven biotechnology company focused on developing novel therapies for serious diseases with high unmet medical need.


The company combines deep biological insight with a strong commitment to translational science, quantitative decision-making, and close cross-functional collaboration.


With an agile culture and ambitious development goals, this environment offers the opportunity to make a visible impact on programs and patients alike.

Key Responsibilities

• Serve as the Clinical Pharmacology lead for assigned clinical programs


• Develop and execute integrated clinical pharmacology plans aligned with overall clinical development strategy


• Design and support clinical pharmacology and PK/PD study protocols


• Perform and/or oversee population PK/PD, PBPK, and other quantitative analyses


• Apply model-informed drug development to support dose selection and compound progression


• Integrate nonclinical, translational, biomarker, and clinical data into coherent modelling strategies


• Interpret emerging PK/PD and biomarker data to inform development decisions


• Contribute to regulatory documents including INDs, IBs, protocols, and briefing packages


• Support regulatory interactions by providing data-driven dose and development justifications


• Collaborate closely with research, toxicology, clinical operations, biometrics, regulatory, and medical teams


• Manage and scientifically oversee CROs and external consultants


• Help build and mentor future clinical pharmacology team members as the function grows

Requirements

• PhD, PharmD, MD, or equivalent degree in pharmacology, pharmaceutical sciences, or a related field


• 10+ years of experience in clinical pharmacology within biotech or pharmaceutical development


• Strong expertise in PK/PD, population modelling, PBPK, dose optimization, and quantitative pharmacology


• Hands-on experience supporting small-molecule drug development programs, including novel therapeutic approaches


• Ability to operate effectively as both an individual contributor and an emerging people leader


• Strong communication, organizational, and cross-functional collaboration skills


• Comfortable working in a fast-paced, growth-stage biotech environment


• Fluency in English; additional languages are a plus